Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation

Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation

As a traditional Chinese medicine-originated disease-modifying anti-rheumatic drug prescription, Baihu-Guizhi decoction (BHGZD) is extensively used for the treatment of rheumatoid arthritis (RA) with a satisfying therapeutic efficacy. Mechanically, our previous data indicated that BHGZD may ameliora...

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Bibliographic Details
Main Authors: Weijie Li, Xia Mao, Xiaoyue Wang, Yudong Liu, Kexin Wang, Congchong Li, Taixian Li, Yanqiong Zhang, Na Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
Baihu-Guizhi decoction
balance of the “inflammation-immune” system
pyroptosis
TLR4-NLRP3 inflammasome signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.743086/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.743086/full

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