Convergent Evolution by Cancer and Viruses in Evading the NKG2D Immune Response
The natural killer group 2 member D (NKG2D) receptor and its family of NKG2D ligands (NKG2DLs) are key components in the innate immune system, triggering NK, γδ and CD8<sup>+</sup> T cell-mediated immune responses. While surface NKG2DL are rarely found on healthy cells, expression is sig...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/12/3827 |