The amyloid precursor protein: beyond amyloid

<p>Abstract</p> <p>The amyloid precursor protein (APP) takes a central position in Alzheimer's disease (AD) pathogenesis: APP processing generates the β-amyloid (Aβ) peptides, which are deposited as the amyloid plaques in brains of AD individuals; Point mutations and duplicati...

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Bibliographic Details
Main Authors: Zheng Hui, Koo Edward H
Format: Article
Language:English
Published: BMC 2006-07-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/1/1/5