Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation
Objective: Cardiovascular diseases (CVDs) are the leading cause of mortality in Western countries. Atherosclerosis is a multi-step inflammatory disease characterized at early stages by accumulation of cholesterol in the arterial wall followed by recruitment of immune cells. We sought to determine if...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-10-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877816300801 |