Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation

Objective: Cardiovascular diseases (CVDs) are the leading cause of mortality in Western countries. Atherosclerosis is a multi-step inflammatory disease characterized at early stages by accumulation of cholesterol in the arterial wall followed by recruitment of immune cells. We sought to determine if...

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Bibliographic Details
Main Authors: Cyrielle Billon, Sadichha Sitaula, Thomas P. Burris
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300801