Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling

Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling

Mohammed F Alotaibi,1 Fakhria Al-Joufi,2 Howida S Abou Seif,3 Mohammed A Alzoghaibi,1 Laiche Djouhri,4 Ahmad F Ahmeda,5 Ayman M Mahmoud6 1Physiology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia; 2Department of Pharmacology, Faculty of Pharmacy, Jouf University, S...

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Bibliographic Details
Main Authors: Alotaibi MF, Al-Joufi F, Abou Seif HS, Alzoghaibi MA, Djouhri L, Ahmeda AF, Mahmoud AM
Format: Article
Language:English
Published: Dove Medical Press 2020-09-01
Series:Drug Design, Development and Therapy
Subjects:
umbelliferone
star
oxidative stress
nrf2
inflammation
pituitary-gonadal axis.
Online Access:https://www.dovepress.com/umbelliferone-inhibits-spermatogenic-defects-and-testicular-injury-in--peer-reviewed-article-DDDT

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https://www.dovepress.com/umbelliferone-inhibits-spermatogenic-defects-and-testicular-injury-in--peer-reviewed-article-DDDT

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