Ultrasensitive norovirus detection using DNA aptasensor technology.

DNA aptamers were developed against murine norovirus (MNV) using SELEX (Systematic Evolution of Ligands by EXponential enrichment). Nine rounds of SELEX led to the discovery of AG3, a promising aptamer with very high affinity for MNV as well as for lab-synthesized capsids of a common human norovirus...

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Bibliographic Details
Main Authors: Amanda Giamberardino, Mahmoud Labib, Eman M Hassan, Jason A Tetro, Susan Springthorpe, Syed A Sattar, Maxim V Berezovski, Maria C DeRosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828344?pdf=render