Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes

Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes

Dengue virus (DENV) is an important human pathogen causing millions of disease cases and thousands of deaths worldwide. Non-structural protein 4A (NS4A) is a vital component of the viral replication complex (RC) and plays a major role in the formation of host cell membrane-derived structures that pr...

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Bibliographic Details
Main Authors: Yu-Fu Hung, Melanie Schwarten, Silke Hoffmann, Dieter Willbold, Ella H. Sklan, Bernd W. Koenig
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Viruses
Subjects:
Dengue virus (DENV)
non-structural protein 4A (NS4A)
amphipathic helix
curvature sensing
peptide membrane interaction
Online Access:http://www.mdpi.com/1999-4915/7/7/2812

Internet

http://www.mdpi.com/1999-4915/7/7/2812

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