Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains

3′,5′-Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which plays critical roles in cardiac function and disease. In adult mouse ventricular myocytes (AMVMs), several distinct functionally relevant microdomains with tightly compartmentalized cAMP signaling have been described....

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Bibliographic Details
Main Authors: Nikoleta Pavlaki, Kirstie A. De Jong, Birgit Geertz, Viacheslav O. Nikolaev, Alexander Froese
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
cAMP
biosensor
cardiac hypertrophy
non-raft sarcolemma
compartmentation
fluorescence resonance energy transfer
Online Access:https://www.mdpi.com/2073-4409/10/3/535

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https://www.mdpi.com/2073-4409/10/3/535

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