Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment

ObjectiveThe aim of this study was to investigate the in vitro and in vivo performance of self-nanoemulsifying drug delivery systems (SNEDDSs) of talinolol (TAL), a poorly water-soluble drug.MethodsSelf-nanoemulsifying drug delivery systems of TAL were prepared using various oils, non-ionic surfacta...

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Bibliographic Details
Main Authors: Mohsin Kazi, Mohammed Al-Swairi, Ajaz Ahmad, Mohammad Raish, Fars K. Alanazi, Mohamed M. Badran, Azmat Ali Khan, Amer M. Alanazi, Muhammad Delwar Hussain
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
self-nanoemulsifying drug delivery systems (SNEDDS)
lipid based formulations (LBFs)
lipid formulation classification system (LFCS)
talinolol
in vitro dissolution
RBC toxicity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00459/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00459/full

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