Quantitative amino acid analysis by liquid chromatography‐tandem mass spectrometry using low cost derivatization and an automated liquid handler

Abstract Amino acid analysis is central to newborn screening and the investigation of inborn errors of metabolism. Ion‐exchange chromatography with ninhydrin derivatization remains the reference method for quantitative amino acid analysis but offers slow chromatography and is susceptible to interfer...

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Bibliographic Details
Main Authors: William S. Phipps, Eric Crossley, Richard Boriack, Patricia M. Jones, Khushbu Patel
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:JIMD Reports
Subjects:
Online Access:https://doi.org/10.1002/jmd2.12080