Genome-wide analysis of natural selection on human cis-elements.

It has been speculated that the polymorphisms in the non-coding portion of the human genome underlie much of the phenotypic variability among humans and between humans and other primates. If so, these genomic regions may be undergoing rapid evolutionary change, due in part to natural selection. Howe...

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Bibliographic Details
Main Authors: Praveen Sethupathy, Hoa Giang, Joshua B Plotkin, Sridhar Hannenhalli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2522239?pdf=render