Novel Lipid-Free Nanoformulation for Improving Oral Bioavailability of Coenzyme Q10

To improve the bioavailability of orally administered lipophilic coenzyme Q10 (CoQ10), we formulated a novel lipid-free nano-CoQ10 system stabilized by various surfactants. Nano-CoQ10s, composed of 2.5% (w/w) CoQ10, 1.67% (w/w) surfactant, and 41.67% (w/w) glycerol, were prepared by hot high-pressur...

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Bibliographic Details
Main Authors: Huafeng Zhou, Guoqing Liu, Jing Zhang, Ning Sun, Mingxing Duan, Zemin Yan, Qiang Xia
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/793879