Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression

<p>Abstract</p> <p>Background</p> <p>Gamma-linolenic acid is a known inhibitor of tumour cell proliferation and migration in both <it>in vitro </it>and <it>in vivo </it>conditions. The aim of the present study was to determine the mechanisms by w...

Full description

Bibliographic Details
Main Authors: Colquhoun Alison, Benadiba Marcel, Miyake Juliano
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/8/1/8