Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model

Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model

Here we examine the organ level toxicology of both carbon black (CB) and silver nanoparticles (AgNP). We aim to determine metal-specific effects to respiratory function, inflammation and potential interactions with lung lining fluid (LLF). C57Bl6/J male mice were intratracheally instilled with salin...

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Bibliographic Details
Main Authors: Danielle Botelho, Bey F. Leo, Christopher Massa, Srijata Sarkar, Terry Tetley, Kian F. Chung, Shu Chen, Mary P. Ryan, Alexandra Porter, Elena N. Atochina-Vasserman, Junfeng Zhang, Stephan Schwander, Andrew J. Gow
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
silver nanoparticles
lung
pulmonary function
surfactant
inflammation
nanoparticles
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00213/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00213/full

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