Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling

Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling

Arginine methyltransferase PRMT7 is associated with human breast cancer metastasis. Endosomal FAK signalling is critical for cancer cell migration. Here we identified the pivotal roles of PRMT7 in promoting endosomal FAK signalling activation during breast cancer metastasis. PRMT7 exerted its functi...

Full description

Bibliographic Details
Main Authors: Yingqi Liu, Lingling Li, Xiaoqing Liu, Yibo Wang, Lingxia Liu, Lu Peng, Jiayuan Liu, Lian Zhang, Guannan Wang, Hongyuan Li, Dong-Xu Liu, Baiqu Huang, Jun Lu, Yu Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
metastasis
endocytosis
methylation
PRMT7
SHANK2
FAK
Online Access:https://elifesciences.org/articles/57617

Internet

https://elifesciences.org/articles/57617

Similar Items