Prevention of tooth extraction-triggered bisphosphonate-related osteonecrosis of the jaws with basic fibroblast growth factor: An experimental study in rats.

Prevention of tooth extraction-triggered bisphosphonate-related osteonecrosis of the jaws with basic fibroblast growth factor: An experimental study in rats.

Osteonecrosis of the jaw induced by administration of bisphosphonates (BPs), BP-related osteonecrosis (BRONJ), typically develops after tooth extraction and is medically challenging. As BPs inhibit oral mucosal cell growth, we hypothesized that suppression of the wound healing-inhibiting effects cou...

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Bibliographic Details
Main Authors: Mitsuhiko Imada, Takahiro Yagyuu, Yoshihiro Ueyama, Masahiko Maeda, Kazuhiko Yamamoto, Satoshi Kurokawa, Jun-Ichiro Jo, Yasuhiko Tabata, Yasuhito Tanaka, Tadaaki Kirita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211928

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https://doi.org/10.1371/journal.pone.0211928

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