In silico screening of FDA approved drugs reveals ergotamine and dihydroergotamine as potential coronavirus main protease enzyme inhibitors

In silico screening of FDA approved drugs reveals ergotamine and dihydroergotamine as potential coronavirus main protease enzyme inhibitors

Coronaviruses with the largest viral genomes are positive-sense RNA viruses associated with a history of global epidemics such as the severe respiratory syndrome (SARS), the Middle East respiratory syndrome (MERS) and recently the coronavirus disease 2019 (COVID-19). There has been no vaccines or dr...

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Bibliographic Details
Main Authors: Arun Bahadur Gurung, Mohammad Ajmal Ali, Joongku Lee, Mohammad Abul Farah, Khalid Mashay Al-Anazi
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Saudi Journal of Biological Sciences
Subjects:
Coronaviruses
Coronaviral main protease
FDA approved drugs
Ergotamine
Dihydroergotamine
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20302461

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http://www.sciencedirect.com/science/article/pii/S1319562X20302461

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