Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations o...

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Bibliographic Details
Main Authors: Abhishek Mitra, Magdalena Skrzypczak, Krzysztof Ginalski, Maga Rowicka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0120520