The Effect of Metformin on Adolescents with Type 1 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background. The effect of metformin in combination with insulin in adolescents with type 1 diabetes (T1DM) is controversial. Methods and Results. The PubMed and EMBASE online databases were searched. Five double-blind randomized controlled trials (RCTs) that included 301 adolescents with T1DM were i...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2016/3854071 |