CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system

Background MYC is one of the proto-oncogenes contributing to tumorigenesis in many human cancers. Although the mechanism of MYC regulation is still not fully understood, learning about the comprehensive mechanism controlling the transcriptional activity of MYC will lead to therapeutic targets. The C...

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Bibliographic Details
Main Authors: Akiko Yamamoto, Morito Kurata, Iichiroh Onishi, Keisuke Sugita, Miwa Matsumura, Sachiko Ishibashi, Masumi Ikeda, Kouhei Yamamoto, Masanobu Kitagawa
Format: Article
Language:English
Published: PeerJ Inc. 2020-05-01
Series:PeerJ
Subjects:
MYC
Online Access:https://peerj.com/articles/9046.pdf