Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction

Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction

Summary: Cannabinoids are reported to rescue cocaine-induced seizures (CISs), a severe complication in cocaine users. However, the molecular targets for cannabinoid therapy of CISs remain unclear. Here, we report that the systemic administration of cannabinoids alleviates CISs in a CB1/CB2-receptor-...

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Bibliographic Details
Main Authors: Guichang Zou, Xin Zuo, Kai Chen, Yushu Ge, Xiaoqun Wang, Guangwei Xu, Huan Wang, Chenjian Miao, Zhenyu Xu, Shuangshuang Tian, Zhen Wang, Yifeng Zhou, Wei Wei, Guangming Huang, Dan Liu, Wei Xiong
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302874

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http://www.sciencedirect.com/science/article/pii/S2211124720302874

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