ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells

ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells

Type IV P-type ATPases (P4-ATPases) translocate phospholipids from the exoplasmic to the cytoplasmic leaflets of cellular membranes. We and others previously showed that ATP11C, a member of the P4-ATPases, translocates phosphatidylserine (PS) at the plasma membrane. Twenty years ago, the UPS-1 (upta...

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Bibliographic Details
Main Authors: Naoto Takada, Hiroyuki Takatsu, Rie Miyano, Kazuhisa Nakayama, Hye-Won Shin
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Journal of Lipid Research
Subjects:
uptake of fluorescent phosphatidylserine analogs
adenosine triphosphatases
membrane bilayer
phospholipid
plasma membrane
flippase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354845

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http://www.sciencedirect.com/science/article/pii/S0022227520354845

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