Liver-specific expression of the <it>agouti </it>gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes

<p>Abstract</p> <p>Background</p> <p>The agouti protein is a paracrine factor that is normally present in the skin of many species of mammals. Agouti regulates the switch between black and yellow hair pigmentation by signalling through the melanocortin 1 receptor (Mc1r)...

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Bibliographic Details
Main Authors: Kiefer Laura L, Klebig Mitchell L, Mynatt Randall L, Kuklin Alexander I, Wilkison William O, Woychik Richard P, Michaud Edward J
Format: Article
Language:English
Published: BMC 2004-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/3/1/17