Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells

Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells

Nuclear Factor kappa B (NF-κB) is a transcription factor family critical in the activation of pro- inflammatory responses. The NF-κB pathway is regulated by oxidant-induced post-translational modifications. Protein S-glutathionylation, or the conjugation of the antioxidant molecule, glutathione to r...

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Bibliographic Details
Main Authors: Jane T. Jones, Xi Qian, Jos L.J. van der Velden, Shi Biao Chia, David H. McMillan, Stevenson Flemer, Sidra M. Hoffman, Karolyn G. Lahue, Robert W. Schneider, James D. Nolin, Vikas Anathy, Albert van der Vliet, Danyelle M. Townsend, Kenneth D. Tew, Yvonne M.W. Janssen-Heininger
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Redox Biology
Subjects:
NF-κB
GSTP
S-glutathionylation
Asthma
Inflammation
Lung
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716300246

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http://www.sciencedirect.com/science/article/pii/S2213231716300246

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