Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells

Abstract Background Paclitaxel well known as anti-cancer drug has been shown to cause alopecia in chemotherapy. The paclitaxel chemotherapy-mediated alopecia is induced by apoptotic damage in human dermal papilla (HDP) cells. Epigallocatechin-3-gallate (EGCG) inhibits apoptosis against anti-cancer d...

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Bibliographic Details
Main Authors: Shang Hun Shin, Hwa Jun Cha, Karam Kim, In-Sook An, Kyung-Yun Kim, Jung-Eun Ku, Sun-Hee Jeong, Sungkwan An
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Biomedical Dermatology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41702-017-0016-1