Tracing Actin Filament Bundles in Three-Dimensional Electron Tomography Density Maps of Hair Cell Stereocilia

Tracing Actin Filament Bundles in Three-Dimensional Electron Tomography Density Maps of Hair Cell Stereocilia

Cryo-electron tomography (cryo-ET) is a powerful method of visualizing the three-dimensional organization of supramolecular complexes, such as the cytoskeleton, in their native cell and tissue contexts. Due to its minimal electron dose and reconstruction artifacts arising from the missing wedge duri...

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Bibliographic Details
Main Authors: Salim Sazzed, Junha Song, Julio A. Kovacs, Willy Wriggers, Manfred Auer, Jing He
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
cryo-electron tomography
image
density
filament
pattern recognition
segmentation
stereocilia
actin
model building
volumetric model
Online Access:http://www.mdpi.com/1420-3049/23/4/882

Internet

http://www.mdpi.com/1420-3049/23/4/882

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