Association of MTHFR Polymorphisms and Chromosomal Abnormalities in Leukemia

Genetic variation in MTHFR gene might explain the interindividual differences in the reduction of DNA repaired and the increase of chromosome breakage and damage. Nowadays, chromosomal rearrangement is recognized as a major cause of lymphoid malignancies. In addition, the association of MTHFR polymo...

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Bibliographic Details
Main Authors: Thivaratana Sinthuwiwat, Phanasit Poowasanpetch, Angsana Wongngamrungroj, Kamonwan Soonklang, Somying Promso, Chirayu Auewarakul, Chintana Tocharoentanaphol
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0862