Lupeol, a Pentacyclic Triterpene, Promotes Migration, Wound Closure, and Contractile Effect In Vitro: Possible Involvement of PI3K/Akt and p38/ERK/MAPK Pathways

Lupeol, a Pentacyclic Triterpene, Promotes Migration, Wound Closure, and Contractile Effect In Vitro: Possible Involvement of PI3K/Akt and p38/ERK/MAPK Pathways

Skin wound healing is a dynamic and complex process involving several mediators at the cellular and molecular levels. Lupeol, a phytoconstituent belonging to the triterpenes class, is found in several fruit plants and medicinal plants that have been the object of study in the treatment of various di...

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Bibliographic Details
Main Authors: Fernando Pereira Beserra, Meilang Xue, Gabriela Lemos de Azevedo Maia, Ariane Leite Rozza, Cláudia Helena Pellizzon, Christopher John Jackson
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
lupeol
keratinocytes
fibroblasts
wound healing
cell migration
Online Access:https://www.mdpi.com/1420-3049/23/11/2819

Internet

https://www.mdpi.com/1420-3049/23/11/2819

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