Cigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammation.

Cigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammation.

Cigarette smoking is an important risk factor for atherosclerosis, a chronic inflammatory disease. However the underlying factors of this effect are unclear. It has been hypothesized that water-soluble components of cigarette smoke can directly promote oxidative stress in vasculature and blood cells...

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Main Authors: Ulisse Garbin, Anna Fratta Pasini, Chiara Stranieri, Mattia Cominacini, Andrea Pasini, Stefania Manfro, Fabio Lugoboni, Chiara Mozzini, GianCesare Guidi, Giovanni Faccini, Luciano Cominacini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2784946?pdf=render

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http://europepmc.org/articles/PMC2784946?pdf=render

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