Role of Desumoylation in the Development of Prostate Cancer

SUMO is a novel ubiquitin-like protein that can covalently modify a large number of nuclear proteins. SUMO modification has emerged as an important regulatory mechanism for protein function and localization. Sumoylation is a dynamic process that is mediated by activating (El), conjugating (E2), and...

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Bibliographic Details
Main Authors: Jinke Cheng, Tasneem Bawa, Peng Lee, Limin Gong, Edward T.H. Yeh
Format: Article
Language:English
Published: Elsevier 2006-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800059