Role of CTLA4 in the proliferation and survival of chronic lymphocytic leukemia.

Earlier, we reported that CTLA4 expression is inversely correlated with CD38 expression in chronic lymphocytic leukemia (CLL) cells. However, the specific role of CTLA4 in CLL pathogenesis remains unknown. Therefore, to elucidate the possible role of CTLA4 in CLL pathogenesis, CTLA4 was down-regulat...

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Bibliographic Details
Main Authors: Amit K Mittal, Nagendra K Chaturvedi, Rae A Rohlfsen, Payal Gupta, Avadhut D Joshi, Ganapati V Hegde, R Gregory Bociek, Shantaram S Joshi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936412/?tool=EBI