Different dose-dependent effects of ebselen in sciatic nerve ischemia-reperfusion injury in rats

Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups...

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Bibliographic Details
Main Authors: Filiz Ozyigit, Aysegul Kucuk, Sezer Akcer, Murat Tosun, Emel Fatma Kocak, Cengiz Kocak, Ahmet Kocak, Hasan Metineren, Osman Genc
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2015-08-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Online Access:http://www.bjbms.org/ojs/index.php/bjbms/article/view/521