Indel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicine

Indel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicine

Abstract Background RNA-seq is the most commonly used sequencing application. Not only does it measure gene expression but it is also an excellent media to detect important structural variants such as single nucleotide variants (SNVs), insertion/deletion (Indels) or fusion transcripts. However, dete...

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Bibliographic Details
Main Authors: Naresh Prodduturi, Aditya Bhagwate, Jean-Pierre A. Kocher, Zhifu Sun
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Medical Genomics
Subjects:
RNA sequencing
Somatic mutations
Insertion/deletion
Fusion transcript
Gene expression
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s12920-018-0391-5

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http://link.springer.com/article/10.1186/s12920-018-0391-5

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