Accurate reconstruction of insertion-deletion histories by statistical phylogenetics.

The Multiple Sequence Alignment (MSA) is a computational abstraction that represents a partial summary either of indel history, or of structural similarity. Taking the former view (indel history), it is possible to use formal automata theory to generalize the phylogenetic likelihood framework for fi...

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Bibliographic Details
Main Authors: Oscar Westesson, Gerton Lunter, Benedict Paten, Ian Holmes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22536326/pdf/?tool=EBI