Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway

Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway

Skeletal muscle atrophy is an important feature of cancer cachexia, which can be induced by chemotherapy, and affects the survival and quality of life of cancer patients seriously. No specific drugs for cancer cachexia have been applied in clinical practice. This study explored the therapeutic effec...

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Bibliographic Details
Main Authors: Hong Zhang, Mengyi Chi, Linlin Chen, Xipeng Sun, Lili Wan, Quanjun Yang, Cheng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
natural products
forkhead box O
muscle atrophy
cachexia
cisplatin
linalool
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.598166/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.598166/full

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