SMART-Q:  An Integrative Pipeline Quantifying Cell Type-Specific RNA Transcription.

Accurate RNA quantification at the single-cell level is critical for understanding the dynamics of gene expression and regulation across space and time. Single molecule FISH (smFISH), such as RNAscope, provides spatial and quantitative measurements of individual transcripts, therefore, can be used t...

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Bibliographic Details
Main Authors: Xiaoyu Yang, Seth Bergenholtz, Lenka Maliskova, Mark-Phillip Pebworth, Arnold R Kriegstein, Yun Li, Yin Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228760