Mechanotransduction of Strain Regulates an Invasive Phenotype in Newly Transformed Epithelial Cells

Our organs and tissues are in constant motion, exposing epithelial cells to mechanical stretch. How these external forces impact cellular morphology, organization and dynamics in healthy and diseased tissues is still being elucidated. Carcinoma, the most common type of cancer, develops in the sheets...

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Bibliographic Details
Main Authors: Sophie Chagnon-Lessard, Hubert Jean-Ruel, Michel Godin, Andrew E. Pelling
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2021.654613/full