AAV-mediated overexpression of the CB1 receptor in the mPFC of adult rats alters cognitive flexibility, social behavior and emotional reactivity

AAV-mediated overexpression of the CB1 receptor in the mPFC of adult rats alters cognitive flexibility, social behavior and emotional reactivity

The endocannabinoid (ECB) system is strongly involved in the regulation of cognitive processing and emotional behavior and evidence indicates that ECB signaling might affect these behavioral abilities by modulations of prefrontal cortical functions. The aim of the present study was to examine the ro...

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Bibliographic Details
Main Authors: Matthias eKlugmann, Anja eGoepfrich, Chris M Friemel, Miriam eSchneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
social interaction
CB1 receptor
emotional reactivity
attentional set shift task
cognitive flexibility
mPFC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00037/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00037/full

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