BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability

BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability

Abstract Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability (CIN), which contributes to the acquisition of heterogeneity, along with MM progression, drug resistance, and relapse. In this study, we elucidated that the expression of...

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Bibliographic Details
Main Authors: Xiaozhu Tang, Mengjie guo, Pinggang Ding, Zhendong Deng, Mengying Ke, Yuxia Yuan, Yanyan Zhou, Zigen Lin, Muxi Li, Chunyan Gu, Xiaosong Gu, Ye Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00746-6

Internet

https://doi.org/10.1038/s41392-021-00746-6

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