Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

<h4>Background</h4>Chronic oral quercetin reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (aglycone) is usually not present in plasma, because it is rapidly metabolized into conjugated, mostly inactive, metabolites. The aim of the s...

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Main Authors: Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22427863/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22427863/?tool=EBI

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