Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice.

Caveolae are omega-shaped plasma membrane micro-domains that are abundant in cells of the vascular system. Formation of caveolae depends on caveolin-1 and cavin-1 and lack of either protein leads to loss of caveolae. Mice with caveolin-1 deficiency have dysfunctional blood vessels, but whether absen...

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Bibliographic Details
Main Authors: Karl Swärd, Sebastian Albinsson, Catarina Rippe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24658465/pdf/?tool=EBI