Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

Abstract Background β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron home...

Full description

Bibliographic Details
Main Authors: Parinaz Zarghamian, Azita Azarkeivan, Ali Arabkhazaeli, Ahmad Mardani, Majid Shahabi
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Genetics
Subjects:
β-Thalassemia
Iron overload
Hepcidin
SNP
Online Access:http://link.springer.com/article/10.1186/s12881-020-01011-3

Internet

http://link.springer.com/article/10.1186/s12881-020-01011-3

Similar Items