Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity.

Berberine, one of the major constituents of Chinese herb Rhizoma coptidis, has been demonstrated to lower blood glucose, blood lipid, and body weight in patients with type 2 diabetes mellitus. The anti-obesity effect of berberine has been attributed to its anti-adipogenic activity. However, the unde...

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Bibliographic Details
Main Authors: Juan Zhang, Hongju Tang, Ruyuan Deng, Ning Wang, Yuqing Zhang, Yao Wang, Yun Liu, Fengying Li, Xiao Wang, Libin Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4415922?pdf=render