Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner

Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner

Abstract This study was designed to evaluate ERK5 expression in lung cancer and malignant melanoma progression and to ascertain the involvement of ERK5 signaling in lung cancer and melanoma. We show that ERK5 expression is abundant in human lung cancer samples, and elevated ERK5 expression in lung c...

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Bibliographic Details
Main Authors: Weiwei Jiang, Fangfang Cai, Huangru Xu, Yanyan Lu, Jia Chen, Jia Liu, Nini Cao, Xiangyu Zhang, Xiao Chen, Qilai Huang, Hongqin Zhuang, Zi-Chun Hua
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:Protein & Cell
Subjects:
ERK5
lung cancer
melanoma
metastasis
FAK
USF1
Online Access:https://doi.org/10.1007/s13238-020-00701-1

Internet

https://doi.org/10.1007/s13238-020-00701-1

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