Transcriptional landscape of cellular networks reveal interactions driving the dormancy mechanisms in cancer

Abstract Primary cancer cells exert unique capacity to disseminate and nestle in distant organs. Once seeded in secondary sites, cancer cells may enter a dormant state, becoming resistant to current treatment approaches, and they remain silent until they reactivate and cause overt metastases. To ill...

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Bibliographic Details
Main Authors: Dilara Uzuner, Yunus Akkoç, Nesibe Peker, Pınar Pir, Devrim Gözüaçık, Tunahan Çakır
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94005-x