New Tetramic Acids Comprising of Decalin and Pyridones From Chaetomium olivaceum SD-80A With Antimicrobial Activity

New Tetramic Acids Comprising of Decalin and Pyridones From Chaetomium olivaceum SD-80A With Antimicrobial Activity

Cycloaddition reactions such as intramolecular Diels–Alder (IMDA) are extremely important in constructing multicyclic scaffolds with diverse bioactivities. Using MycB as a biomarker, three new polyketides – Chaetolivacines A (1), B (3), and C (4) – with one known compound Myceliothermophin E (2) com...

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Bibliographic Details
Main Authors: Xinzhu Wang, Liya Zhao, Chao Liu, Jun Qi, Peipei Zhao, Zhaoming Liu, Chunlei Li, Yingying Hu, Xin Yin, Xin Liu, Zhixin Liao, Lixin Zhang, Xuekui Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
Chaetomium olivaceum
tetramic acids
isolation
anti-MRSA
biosynthesis pathway
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02958/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02958/full

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