Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants

Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants

A growing body of evidence indicates that miRNAs may either drive or suppress oncogenesis. However, little is known about somatic mutations in miRNA genes. To determine the frequency and potential consequences of miRNA gene mutations, we analyzed whole exome sequencing datasets of 569 lung adenocarc...

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Bibliographic Details
Main Authors: Paulina Galka-Marciniak, Martyna Olga Urbanek-Trzeciak, Paulina Maria Nawrocka, Agata Dutkiewicz, Maciej Giefing, Marzena Anna Lewandowska, Piotr Kozlowski
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
miRNA
somatic mutations
lung cancer
TCGA
non-coding
Online Access:https://www.mdpi.com/2072-6694/11/6/793

Internet

https://www.mdpi.com/2072-6694/11/6/793

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