Ezetimibe: Its Novel Effects on the Prevention and the Treatment of Cholesterol Gallstones and Nonalcoholic Fatty Liver Disease

The cholesterol absorption inhibitor ezetimibe can significantly reduce plasma cholesterol concentrations by inhibiting the Niemann-Pick C1-like 1 protein (NPC1L1), an intestinal sterol influx transporter that can actively facilitate the uptake of cholesterol for intestinal absorption. Unexpectedly,...

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Bibliographic Details
Main Authors: Ornella de Bari, Brent A. Neuschwander-Tetri, Min Liu, Piero Portincasa, David Q.-H. Wang
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Lipids
Online Access:http://dx.doi.org/10.1155/2012/302847