Manipulation of the porcine epidemic diarrhea virus genome using targeted RNA recombination.

Porcine epidemic diarrhea virus (PEDV) causes severe economic losses in the swine industry in China and other Asian countries. Infection usually leads to an acute, often lethal diarrhea in piglets. Despite the impact of the disease, no system is yet available to manipulate the viral genome which has...

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Bibliographic Details
Main Authors: Chunhua Li, Zhen Li, Yong Zou, Oliver Wicht, Frank J M van Kuppeveld, Peter J M Rottier, Berend Jan Bosch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732256?pdf=render