Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?

Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?

Objective(s): Neuroprotection is created following the inhibition of angiotensin II type 1 receptor (AT1R). Therefore, the purpose of this research was examining AT1R blockage by candesartan in diffuse traumatic brain injury (TBI). Materials and Methods: Male rats were assigned into sham, TBI, vehic...

Full description

Bibliographic Details
Main Authors:	Mohammad Khaksari, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Zahra Soltani, Sina Motamedi, Fatemeh Moramdi, Masoud Islami, Shahriyar Shafa, Sepehr Khosravi
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2018-06-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Angiotensin II receptor Blood-brain barrier Brain edema Brain injury Candesartan Intracranial pressure Lipid peroxidation
Online Access:	http://ijbms.mums.ac.ir/article_10694_0a2ad7a22d187d10470a8d705e98ff92.pdf

Similar Items

The effect of angiotensin receptor type 2 inhibition and estrogen on experimental traumatic brain injury
by: Mojdeh Hajmohammadi, et al.
Published: (2018-01-01)

The Effect of Candesartan Alone and Its Combination With Estrogen on Post-traumatic Brain Injury Outcomes in Female Rats
by: Mojdeh Hajmohammadi, et al.
Published: (2019-12-01)

Aqueous Date Fruit Efficiency as Preventing Traumatic Brain Deterioration and Improving Pathological Parameters after Traumatic Brain Injury in Male Rats
by: Hamze Badeli, et al.
Published: (2016-09-01)

Effects of the Combination Therapy with ‍Candesartan and Alpha Tocopherol on Brain injury and Edema Following Brain Ischemia in Experimental Model of Transient Focal Cerebral Ischemia in Rats
by: Hamdollah Panahpour, et al.
Published: (2016-07-01)

The Effects of Shilajit on Brain Edema, Intracranial Pressure and Neurologic Outcomes following the Traumatic Brain Injury in Rat
by: Mohammad Khaksari, et al.
Published: (2013-07-01)

Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways
by: Peter J. Attilio, et al.
Published: (2021-03-01)

Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury
by: Nader Shahrokhi, et al.
Published: (2018-03-01)

Intracranial pressure monitoring in severe traumatic brain injury
by: Al. Cosmin Apetrei, et al.
Published: (2014-06-01)

The aqueous interchange's condition in case of cerebrovascular pathology
by: Yu. I. Borodin, et al.
Published: (2009-06-01)

Estrogen provides neuroprotection against brain edema and blood brain barrier disruption through both estrogen receptors α and β following traumatic brain injury
by: Vida Naderi, et al.
Published: (2015-02-01)

EFFECTS OF L-LYSINE AESCINAT ON INTRACRANIAL PRESSURE IN CRITICALLY ILL PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY
by: S. S. Petrikov, et al.
Published: (2016-06-01)

Angiotensin II Receptor 1 Blockage Limits Brain Damage and Improves Functional Outcome After Brain Injury in Aged Animals Despite Age-Dependent Reduction in AT1 Expression
by: Ralph Timaru-Kast, et al.
Published: (2019-04-01)

Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Tlr2/4−/− Mice
by: Sandro M. Krieg, et al.
Published: (2017-08-01)

Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats
by: Forouzan Frozandeh, et al.
Published: (2021-06-01)

Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
by: Fernando Mendes Paschoal Junior, et al.

Emergent Decompressive Craniectomy in Patients with Fixed Dilated Pupils; A Single Center Experience
by: Luis Rafael Moscote-Salazar, et al.
Published: (2013-10-01)

The Pathophysiology of Brain Edema and Intracranial Hypertension
by: Jin-Heon Jeong
Published: (2016-12-01)

The Role of Substance P in Secondary Pathophysiology after Traumatic Brain Injury
by: Robert Vink, et al.
Published: (2017-06-01)

Effects of different phases of estrous cycle on brain edema and neurological outcomes after severe traumatic brain injury in female rats
by: Ali Siahposht khachaki, et al.
Published: (2011-10-01)

Blockade of Central Angiotensin II AT1 Receptor Protects the Brain from Ischemia/Reperfusion Injury in Normotensive Rats
by: Hamdolah Panahpour, et al.
Published: (2014-10-01)

Early mannitol administration improves clinical outcomes of pediatric patients with brain edema
by: Putu A. Sekarningrum, et al.
Published: (2018-12-01)

Differential clinical profile of candesartan compared to other angiotensin receptor blockers
by: Zimlichman R
Published: (2011-12-01)

An Experimental Study of Relationship Between Magnetic Induction Phase Shift and Brain Parenchyma Volume With Brain Edema in Traumatic Brain Injury
by: Shuanglin Zhao, et al.
Published: (2019-01-01)

The effect of sex steroid hormones on brain edema and intracranial pressure after experimental traumatic brain injury in rats
by: Nader Shahrokhi, et al.
Published: (2008-08-01)

Effects of craniopuncture and drainage of intracerebral hemorrhage on brain edema and neurological outcome
by: Xueyuan WANG, et al.
Published: (2011-04-01)

Extrusion of Intracranial Tumor Mass—A Rare Phenomenon
by: Charandeep S Gandhoke, et al.
Published: (2018-01-01)

Massive cerebral edema resulting in brain death as a complication of Cryptococcus neoformans meningitis
by: Jose Orsini, et al.
Published: (2015-02-01)

POSSIBILITY OF ANGIOTENSIN RECEPTOR BLOCKERS IN OPTIMIZING OF ANTIHYPERTENSIVE PHARMACOTHERAPY IN PATIENTS AFTER STROK
by: Z M. Sizova
Published: (2015-09-01)

Regional cooling for reducing brain temperature and intracranial pressure Resfriamento cerebral regional para redução da temperatura e pressão intracraniana
by: Luis Vicente Forte, et al.
Published: (2009-06-01)

Editorial: The Role of the Renin-Angiotensin System in the Central Nervous System
by: Natalia P. Rocha, et al.
Published: (2021-07-01)

The Iatrogenic Development of an Anterior Cerebral Artery Pseudoaneurysm during Lamina Terminalis Fenestration–Genesis, Diagnosis and Therapy: Lessons Learned
by: Bartoš Robert, et al.
Published: (2020-06-01)

Optic nerve sheath diameter change in prediction of malignant cerebral edema in ischemic stroke: an observational study
by: Seong-Joon Lee, et al.
Published: (2020-09-01)

Anti-edema effect of Aloe vera leaf extract following traumatic brain injury: Role of pro-inflammatory cytokines
by: Marzieh Shahryari, et al.
Published: (2021-07-01)

Pseudo-subarachnoid hemorrhage sign associated with severe cerebral edema
by: B De Keyzer, et al.
Published: (2014-05-01)

The neuroprotective effect of Cassia o btusifolial extract in rats following TBI
by: Qian-Feng Qiao, et al.
Published: (2020-10-01)

Peritumoral brain edema in intracranial meningiomas Edema peritumoral em meningiomas intracranianos
by: Nelson de Azambuja Pereira-Filho, et al.
Published: (2010-06-01)

Current aspects of the interactions between dementia, the brain renin-angiotensin system and oxidative stress
by: Serban Dragomir, et al.
Published: (2015-01-01)

Neuroprotective effects of bloodletting at Jing points combined with mild induced hypothermia in acute severe traumatic brain injury
by: Yue Tu, et al.
Published: (2016-01-01)

Study of the AQP4 expression in traumatic brain edema and multimodal MRI imaging
by: Li Ai, et al.
Published: (2020-09-01)

Angiotensin-(1-7) and Mas receptor in the brain
by: Natalia L. Rukavina Mikusic, et al.
Published: (2021-06-01)